Reletter
Artwork for Overmatter

Where medicine, politics and tech collide

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Substack
PricingOnly free issuesPublishesMonthly
Issues387Founded5 years agoLast Issuea month ago
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Latest Issues

American boomers were drinking for two-and covering the signs of a generation that quietly stopped drinking.

Ai generated: Perplexity, Mountain made of bottles of alcohol

Spend any time at a work social or a school event and it is hard not to notice that people are not drinking as much. It may even be entirely alcohol free. Something has changed...

a month ago
3
5

When doctors can’t help, the internet will. That’s a problem.

At around 2am, when you are awake for the third night running and the world around you is resting peacefully, a particular kind of fear and hopelessness can take hold. For yet others, it is the gym sessions that have stopped working, and th...

2 months ago
6

We evolved to drink. Now we're trying to stop.

AI generated: drinking glass with figs

The bottom line? Ten million years of evolutionary loyalty won’t evaporate overnight, but change is coming one functional mocktail at a time. What do you think about the future of drinking? Let me kno...

3 months ago
12
36

In Brief #2: an update on a recent furore

At the end of last week some of my tweets went viral. Since then, another Substack has made a number of untrue assertions about my views and professional conduct. I have written the Substack setting out specific factual inaccuracies and hav...

3 months ago
4
1

In Brief #1: The lab with no lab. How AI is changing the rules of drug discovery

AI: desk nerd designing a molecule on a computer

The first time I truly realised AIs were re-writing the rules of pharma was last year: I was standing in a lab with no lab in it. No benches, no pipettes or odd smells, just a man in black i...

3 months ago
2
4

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Authors

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  • Natasha Loder

    Health Editor, The Economist

  • Anne Philippi

    Founder of The New Health Club Podcast & The New Health Institute

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