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Perambulations

Nathaniel Hendrix

Circular thoughts on meta-science, technology, and healthcare.

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Substack
PricingOnly free issuesPublishesWeekly
Issues23Founded3 years agoLast Issue2 years ago
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Latest Issues

There is a world within the world

Note: This was originally written for the ACX annual book review contest. It didn’t make it into the set of finalists, so I’m posting it here.

1.

For reasons that still aren’t clear, the years following World War 2 were marked in Am...

2 years ago
4
1

The road to an R01

If you want to understand the world of NIH grants, you could do worse than to use the lens of Darwinian evolution. Each mechanism has developed to occupy a niche where it can survive under dual selection pressures: first, it has to provide...

2 years ago
1

What's the effect of age on physician ability?

Note: This topic intersects a little with my day job, so it’s a good time to remind you that the opinions here are mine alone.

The wealthy world’s physicians are getting older as part of the broad demographic shift we’re undergoing. People...

2 years ago
7

Policy should be adaptive

I first really internalized the game theory concept of equilibrium when I started driving in Washington, DC during the summer of 2022. I’d just moved here from Seattle, where the streets are laid out in a grid and drivers are generally calm...

2 years ago
1

Seeing like a system

For a long time, I harbored the suspicion that systems thinkers were just dressing up banal ideas with specialized vocabulary. Then the phrase “The purpose of a system is what it does” started trending on X, which struck me as a pithy expre...

2 years ago
4

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  • Nathaniel Hendrix

    Data scientist and researcher focused mostly on epidemiology, real world evidence, clinical artificial intelligence, and meta-science.

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