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Rational Psychiatry

Thomas Reilly

A monthly newsletter about psychiatric research.

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Substack
PricingOnly free issuesPublishesMonthly
Issues58Founded4 years agoLast Issue17 days ago
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Latest Issues

For your attention, July 2026

Journals

  1. Transition time from manic and mixed episodes to depression: a retrospective cohort study

There is something compelling about the phenotype of bipolar disorder. It was described (as manic depressive insanity) by Emil Kraep...

17 days ago
18
8

Is rebound psychosis a thing?

‘Rebound’ on abruptly stopping medication exists across medicine. Stoping anti-hypertensives will shoot your blood pressure up, above its baseline level. Stopping anti-epileptic medication rapidly lowers the seizure threshold. Stopping beta...

23 days ago
32
36

For your attention, June 2026

Journals

  1. Genetic architecture of postpartum psychosis: from common to rare genetic variation

Postpartum psychosis is considered a ‘psychiatric emergency’ due to the sudden onset following childbirth, fluctuation in symptoms, and ri...

a month ago
24
7

Are British psychiatrists racist, or not?

‘Why anti-racism kills’ was the headline in The Spectator. Similar sentiments were expressed in Unherd, The Telegraph, Wrong Side of History, and GB News. All refer to the Nottingham attacker, Valdo Calocane, who killed three people and inj...

2 months ago
25
11

For your attention, May 2026

Journals

  1. Women and psychosis: a guide to evidence-based, hormone-informed care. My colleague Bodyl Brand has written a Lancet Psychiatry article (I’m a co-author), arguing that our approach to psychosis cannot be sex-neutral. We nee...
3 months ago
24
6

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  • Thomas Reilly

    I'm a psychiatrist doing a DPhil at the University of Oxford, interested in how hormones affect mental health. These view do not represent my employers, funders, or professional bodies. Leave me anonymous feedback - admonymous.co/thomasreilly

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