Stop and Think
John MandrolaA skeptical but not cynical view of scientific evidence
| Platform |  | Pricing | Freemium | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 67 | Subscribers | Read | johnmandrola.substack.com |
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Latest Issues
Recent posts by this newsletter. Browse the email archive.
Older cardiology trials were often hugely positive. Newer cardiology trials not so much
I wrote yesterday over at Sensible Medicine about the RALES (circa 1999) trial of spironolactone vs placebo in patients with heart failure. Patients treated in the spironolactone arm had an 11% lower rate of death. The number needed to save...
Links to My Recent Writing and Speaking
#### Statin Use and the New Risk Calculator
I Might Have Been Wrong About Pulsed Field Ablation for Atrial Fibrillation
Hi everyone. I’ve been stunned about all the new subscribers. I am not sure what happened, but thank you for signing up.
How do Dubious Norms Get Established?
One area continues to dominate my field of cardiology. It is the search for and treatment of ischemic heart disease. Coronary heart disease dominates the minds of patients and doctors alike.
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Authors
The writers behind this newsletter.
Heart rhythm doc, writer/podcaster for @Medscape, learner, cyclist, married to an #HPM doctor. #MedicalConservative. The more you see, the harder medicine gets
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