Reletter
Artwork for Stop and Think

Stop and Think

John Mandrola
Hundreds of paid subscribers

A skeptical but not cynical view of scientific evidence

Platform
Substack
PricingFreemiumPublishesWeekly
Issues84Founded5 years agoLast Issue3 months ago
Active

Read this Newsletter

johnmandrola.substack.com
Artwork for Stop and Think

Latest Issues

Industry vs Non-Industry Funding for Science

Look at this recent post on X:

Dr Holly Morgan is cardiologist and researcher in the UK and was an author on one of the best cardiology trials of our time—the REVIVED BCIS2 trial.

Dr Sunil Rao is a cardiologist and researcher who has pu...

3 months ago
62
15

Some Year End Things and A Pro-Tip

Here’s another update of things I’ve worked on.

My year end review of top cardiovascular stories is up over at TheHeart.org | Medscape Cardiology. We learnt quite a bit in 2025.

  • Two trials suggested less-is-more when it comes to com...
5 months ago
75
11

What I believe in Medicine

Dr. Bryan Vartabedian has a great post on 75 things he believes about medicine. Do read it. There are many gems. Bryan and I started our careers at about the same time.

Stop and Think is a reader-supported publication. To receive new post...

6 months ago
146
21

A Fall Update of My Work Outside of the EP Lab

The mornings in Louisville have grown colder. Our 5 AM thumper of a 40-mile bike ride has given way to the indoor trainer. My brain has more time to write and think in the early mornings.

Here is review of my writing, podcasting and academ...

6 months ago
45
9

Medical evidence should not be too technical for doctors

I debated two key opinion leaders last week. I will tell you topic later; it doesn’t matter for what I want to argue now.

In both debates, my academic colleagues did not focus on the evidence underpinning the procedure. They mentioned evi...

7 months ago
146
31

Key Facts

Contact Information
Newsletter Author
Number of Subscribers
Find out how many people subscribe to this newsletter.

Audience Metrics

Subscribers, engagement, traffic and sponsorship for Stop and Think .

SubscribersEngagement76Monthly Web Visits
Accepts SponsorsEstimated Cost per Ad

Chart Rankings

How this newsletter ranks in the official Substack charts.

#78
Substack
/Science(Paid)

Authors

The writers behind this newsletter.

  • John Mandrola

    Heart rhythm doc, writer/podcaster for @Medscape, learner, cyclist, married to an #HPM doctor. #MedicalConservative. The more you see, the harder medicine gets

  • Social

    Frequently Asked Questions

    How can I access the email archive for Stop and Think ?

    You can find recent issues that have been published by Stop and Think on Reletter by scrolling up to where it says Latest Issues. Tap on the link for any of the most recent emails or hit More Issues to see older ones.

    How many subscribers does Stop and Think have?

    To see how many people subscribe to Stop and Think , simply upgrade your Reletter account. We provide readership numbers and lots of other stats for this newsletter so you can decide if it's worth reaching out to.

    How can I advertise in Stop and Think ?

    Newsletter advertising can be extremely effective when it's done right. Before you pitch Stop and Think as a potential sponsor or partner, make sure that you've done your research and checked its newsletter stats with Reletter.

    Then, personalize one of our winning pitching templates and send it to the right person using the contact info provided.

    How much does it cost to sponsor a publication like Stop and Think ?

    Newsletter ad rates (or CPM) vary depending on many factors, including industry, number of subscribers, open rate, ad placement and more.

    To find out how much an ad will cost, contact Stop and Think using the contact information provided and ask for a copy of their media kit.

    How can I find newsletters related to Stop and Think ?

    Scroll up to where it says Related Newsletters to see other publications like Stop and Think . You can also search our email newsletter directory to discover other newsletters that cover the topics you're interested in.

    How do I contact Stop and Think ?

    Reletter provides this newsletter's website URL above, where you will often find their contact information. We also provide links to associated social media accounts and pitching templates so you can reach out fast.