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The business, science, and policy of kidney health. Read by 20,000+ clinicians, operators, advocates, and policy makers across 65+ countries.

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Latest Issues

Mapping the Next Wave of Kidney Care and CKM Innovation

Some of the most interesting work in kidney care and cardio-kidney-metabolic (CKM) is happening in companies most people haven’t heard of yet: small, early-stage teams building new tools for dialysis access, transplantation, early detection...

6 days ago
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Signals Monthly: September 2026

Illustration: Sarah Grillo/Axios. Adapted by Signals.

September brought a new round of long-awaited approvals and new questions about early screening and prevention, from communities to Capitol Hill. Signals is your monthly digest of the n...

8 days ago
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What space can teach us about kidneys

I first came across Dr. Keith Siew’s work through a paper with a title that was pretty hard to ignore: “Cosmic kidney disease.” For someone who writes a newsletter named for two passions, kidneys and space, this paper was a dream come true....

15 days ago
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Lessons from La Sorbonne

The Sacred Wood, the monumental mural overlooking the Sorbonne’s Grand Amphitheatre, depicting allegorical figures of the Sorbonne, Eloquence, Poetry, Philosophy, History, Botany, Geology, Physics, and Geometry.

A few hundred people from d...

a month ago
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Signals Monthly: August 2026

August brought a full slate of guideline updates, trial data, and dealmaking. Signals is your monthly digest of the news, research, and people shaping kidney health. Thank you for being part of it, and consider joining our new Member Networ...

a month ago
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Authors

The writers behind this newsletter.

  • Tim Fitzpatrick

    Founder, writer, and investor in kidney and CKM health. Author of the leading newsletter on kidney innovation. Building the first dedicated venture fund in the space. Former medtech CEO, US Navy, and TMT trader. Learn more at trfitzpatrick.com

  • Janis Naeve

    Janis Naeve is a scientist, investor, and healthcare strategist with experience across biotech, venture capital, and care delivery. She focuses on how data, policy, and clinical practice intersect to improve outcomes in chronic disease.

  • Gaia Cantelli

    Director of Data Science and NURTuRE at Kidney Research UK

  • Jennifer McKenzie

    Pediatric drug development strategy and execution, pediatric nephrologist, focused on accelerating delivery of new therapies to children with kidney disease.

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