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WMC Research

Walter M Chesnut
Hundreds of paid subscribers

COVID-19 Research

Platform
Substack
PricingOnly free issuesPublishesTwice weekly
Issues558Founded5 years agoLast Issue8 days ago
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Latest Issues

The Spike Protein, Macrophages and the Induction of Systemic Senescence

The word of the day is Paracrine.

There is a fascinating article published in August 2024 in the journal Ageing Research Reviews. It discusses how Long COVID may be seen as a disease of accelerated aging. Of course, we have known this sinc...

8 days ago
42
8

Friday Hope: Piperlongumine (PL): Selectively Kills Both SARS-CoV-2-Infected Cells and Senescent Cells

Today I would like to discuss an alkaloid isolated from Piper longum, or the Long Pepper Plant. The fruit of this plant was used more as a spice in antiquity, though it was also known to be a medicine. Today it is considered for its therape...

11 days ago
43
1

The Macrophage–Cancer Bridge: An Inquiry into Cancers in Unexpected Populations

When we think about cancer, we tend to think about mutations within cancer cells.

But cancer does not develop in isolation.

The surrounding tissue microenvironment can determine whether damaged or abnormal cells survive, proliferate and u...

15 days ago
40
6

Friday Hope: Acacetin: Inhibiting Spike, Protecting the Endothelium and Taming the Macrophage

Acacetin is a flavone which, surprisingly, is NOT a household word. You will generally only encounter “Acacetin” if you are reading peer-reviewed biochemistry journals, studying traditional plant-based medicines, or working in organic chemi...

18 days ago
38
5

The Spike Feed-Forward Loop: Endothelial Activation/Dysfunction and Leukocyte-Endothelial Adhesion

As readers of this Substack know, I have maintained that SPED (Spike Protein Endothelial Disease) is just an early step in the Spike Protein’s systemic assault on the body. Today we can move this hypothesis forward with a look at a more adv...

22 days ago
41
12

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  • Walter M Chesnut

    The only compensation I receive for my research is via donation. Please consider donating via paid subscription here, or via PayPal at https://wmcresearch.org/donate/

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