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Alex Kesin's Pharmacopoeia

Alex Kesin

Ruminations about biotech and drug development - one overly earnest blog post at a time.

Platform
Substack
PricingFreemiumPublishesWeekly
Issues37SubscribersRead alexkesin.com

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Latest Issues

Recent posts by this newsletter. Browse the email archive.

Anti-Amyloids and Antichrist

Some thoughts on Peter Thiel's view of the beta-amyloid hypothesis as a lens for understanding the messy, slow cost of figuring out how to make drugs for complex diseases.

a month ago
5
0
Paid

A Better Proxy Than the Rat and Dog

Disclosure: This profile was commissioned by Axiom Bio. The company provided access to its offices, team, and partner meetings and reviewed drafts for factual accuracy.

2 months ago
32
7

Would Walter White Still Cook Meth in 2025?

You know what’s a fun way to spend a morning? Calculating whether a fictional chemistry teacher’s cancer would be treatable with modern targeted therapy and whether his employer health plan would cover it. I have done this. Let me tell you ...

3 months ago
159
10

Fun with FGF21

In September 2021, Bristol Myers Squibb discontinued development of pegbelfermin, a PEGylated version of a hormone called FGF21, after spending years and probably hundreds of millions of dollars testing it in patients with liver disease. Th...

5 months ago
22
5

Authors

The writers behind this newsletter.

  • Alex Kesin

    I write about drugs (the legal kind).

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