Alex Kesin's Pharmacopoeia
Alex KesinRuminations about biotech and drug development - one overly earnest blog post at a time.
| Platform |  | Pricing | Freemium | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 37 | Founded | 6 years ago | Last Issue | 4 months ago |
| Active | |||||
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alexkesin.comLatest Issues
Anti-Amyloids and Antichrist
Some thoughts on Peter Thiel's view of the beta-amyloid hypothesis as a lens for understanding the messy, slow cost of figuring out how to make drugs for complex diseases.
Last May, during a conversation with Ross Douthat, Peter Thiel turn...
A Better Proxy Than the Rat and Dog
Disclosure: This profile was commissioned by Axiom Bio. The company provided access to its offices, team, and partner meetings and reviewed drafts for factual accuracy.
Consider the hepatocyte. It is a polyhedral thing, roughly twen...
Would Walter White Still Cook Meth in 2025?
You know what’s a fun way to spend a morning? Calculating whether a fictional chemistry teacher’s cancer would be treatable with modern targeted therapy and whether his employer health plan would cover it. I have done this. Let me tell you...
Fun with FGF21
In September 2021, Bristol Myers Squibb discontinued development of pegbelfermin, a PEGylated version of a hormone called FGF21, after spending years and probably hundreds of millions of dollars testing it in patients with liver disease. Th...
How Amgen Lost The PCSK9 Patent War
Patent law rests on a simple covenant: inventors reveal their secrets, and society grants them temporary monopolies in return. But some companies want the monopoly without the showing. They want the treasure. They don’t want to draw the map...
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Authors
The writers behind this newsletter.
I write about drugs (the legal kind).
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