Reletter
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Rough Diamonds

Sarah Constantin
Hundreds of paid subscribers

Underrated opportunities in science, technology, and society

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Substack
PricingFreemiumPublishesWeekly
Issues145Founded5 years agoLast Issue2 months ago
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Latest Issues

FW26 Color Stats

Once again, I am coming out with stats on the colors in the latest fashion collections: this time, for the fall/winter 2026 season.

Previous entries: SS26, FW25, SS25, FW24, SS24.

Methodology Recap

As I’ve done before, I’m using my a...

2 months ago
24

Things that Go Boom

Workers at the Naval Surface Warfare Center in Indian Head, Maryland, the only facility where torpedo fuel is produced for the U.S. Navy

In the event of a late-2020s Chinese attempt to invade Taiwan, leading to a US-China military conflict...

2 months ago
34
10

Getting Back To It

Artist: Lily Taylor

It’s been a while since I’ve written anything lately, and that doesn’t feel good. My writing voice has always been loadbearing to my identity, and if I don’t have anything to say, if I’m not “appearing in public”, it’s...

3 months ago
75
24

Biotech Startup Stats

One thing Claude Code has really made too cheap to meter is data analysis. If you have a question that statistics could shed light on, and there’s relevant public data online, you can now get your answer frictionlessly.

One thing I’d been...

3 months ago
22
7

Cancer-Selective, Pan-Essential Targets from DepMap

Introduction

Back in June, I proposed that it would be a good idea to look for broad-spectrum cancer treatments — i.e. therapies that work on many types of cancer, rather than being hyper-specialized for narrow subtypes.

There’s noth...

4 months ago
22
4

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Authors

The writers behind this newsletter.

  • Sarah Constantin

    science/tech writer and researcher, ex-Nanotronics, Recursion, Palantir, math PhD

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