Polypharmacy
Nils Wendel, MD, Kevin Kennedy, MDRationalist-adjacent musings on psychiatry
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 38 | Founded | 3 years ago | Last Issue | 11 days ago |
| Active | |||||
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polypharmacy.substack.comLatest Issues
We should stop running psychiatric clinical trials that cannot change practice
There are few medications that reflect the messiness of evidence in psychiatry more than prazosin, the old anti-adrenergic blood pressure medication that, as was hounded into me during my training, is synonymous with the treatment of PTSD-r...
One Year of Being An Attending
July 1st marked the passage of my first full year as an attending. I thought it might be useful for me, and perhaps interesting to you, to reflect a little on my experiences over the past year.
Teaching Is Still Fun
This is a relief....
Should we prescribe antidepressants like statins?
What does it mean for a medication to work? If, like me, you have an interest in evidence-based medicine, you would turn to randomized controlled trials (RCTs) to determine whether a medication has specific effects beyond those seen with a...
Seems Like Psychiatrists Should Probably Know About Modern Personality Theory: Part 1
What constitutes someone’s personality?
Despite the fact that the answer to this question bears heavily on both our abstract diagnostic concepts and our practical decisions when it comes to diagnosing and treating individual patients,...
The new "chemical imbalance" myth for depression
Hi everyone,
With this essay I’m thrilled to introduce you all to a new writer for Polypharmacy, Dr. Kevin Kennedy, a fellow psychiatrist. Some of you may have already read some of Kevin’s work over at Thinking Psychiatry, or you may recog...
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| Subscribers | Engagement | 75 | Monthly Web Visits | ||
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Authors
The writers behind this newsletter.
Psychiatrist, independently minded to a troublesome degree. Occasionally produces original thoughts worth sharing.
An academic psychiatrist trying to improve the quality of evidence in psychiatry. For humility. Against hype and bad science. All views my own. “A cynic is a man who knows the price of everything, and the value of nothing.”
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