A review of clinical trials in cardiovascular medicine that have had a major impact on the field. The trials are indexed according to major subject headings and presented in chronological order of publication date.
| Platform |  | Pricing | Freemium | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 188 | Founded | 2 years ago | Last Issue | 7 days ago |
| Active | |||||
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cardiologytrials.substack.comLatest Issues
Review of the ATHENA Trial
N Engl J Med 2009;360:668-678.
Background: Atrial fibrillation is the most common sustained cardiac arrhythmia, with a U.S. prevalence approaching 1% overall and rising to 9% in patients over 80 years of age. Hospitalizations for atrial fi...
Review of the ANDROMEDA Trial
N Engl J Med 2008;358:2678-2687
Background: By the mid-2000s, the management of arrhythmias in heart failure rested on a difficult therapeutic compromise. Atrial fibrillation and ventricular arrhythmias were common in patients with reduced...
Review of the RACE II Trial
N Engl J Med 2010;362:1363-1373
Background: By 2005, the rate-versus-rhythm debate in atrial fibrillation had been largely settled by AFFIRM and the original RACE trial. Both showed that a rhythm-control strategy offered no survival advant...
Review of the SAFE-T Trial
N Engl J Med 2005;352:1861-1872
Background: The optimal drug strategy for the conversion and maintenance of sinus rhythm in patients with atrial fibrillation is debated. AFFIRM and RACE had recently shown in 2002 that a rhythm-control stra...
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A review of major clinical trials in cardiovascular medicine.
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