A review of clinical trials in cardiovascular medicine that have had a major impact on the field. The trials are indexed according to major subject headings and presented in chronological order of publication date.
| Platform |  | Pricing | Freemium | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 211 | Founded | 3 years ago | Last Issue | 5 days ago |
| Active | |||||
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Review of the SHAM-PVI trial
JAMA. 2024;332(14):1165-1173
Background: Pulmonary vein isolation (PVI) for atrial fibrillation (AF) is a frequently performed procedure. At the time of writing this review, it’s estimated that over 100,000 AF ablation procedures are perfo...
Review of the CASTLE-HTx trial
N Engl J Med. 2023;389(15):1380-1389.
Background: Catheter ablation was tested in patients with atrial fibrillation (AF) and heart failure (HF). However, prior trials, notably in CASTLE-AF and RAFT-AF, didn’t include patients with advanced...
Review of the RAFT-AF trial
Circulation 2022;145:1693-1704
Background: Atrial fibrillation (AF) and heart failure (HF) frequently coexist. Patients with both conditions carry worse prognosis than patients with either condition alone. Pharmacologically based rhythm c...
Review of the EARLY-AF trial
N Engl J Med. 2021;384(4):305-315.
Background: At the time of this trial, the recommended initial rhythm control strategy for symptomatic atrial fibrillation (AF) was anti-arrhythmic drugs with catheter ablation reserved for patients in wh...
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A review of major clinical trials in cardiovascular medicine.
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