A review of clinical trials in cardiovascular medicine that have had a major impact on the field. The trials are indexed according to major subject headings and presented in chronological order of publication date.
| Platform |  | Pricing | Freemium | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 217 | Founded | 3 years ago | Last Issue | 4 days ago |
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Review of the SPAF trial
Circulation 1991; 84:527–539
Background: Prior studies showed that treatment with Warfarin reduces the risk of stroke and transient ischemic attacks in patients with non-rheumatic atrial fibrillation. The Stroke Prevention in Atrial Fibril...
Review of the AFASAK trial
Lancet 1989;1:175-179
Background: Atrial fibrillation is a common arrhythmia with a prevalence of about 1-2% in the United States, and its incidence increases with age. The primary concern associated with atrial fibrillation is stroke. The...
Review of the PVI-SHAM-AF trial
Lancet 2026;408:999-1009
Background: Guidelines recommend catheter ablation for symptom relief in atrial fibrillation (AF), but the evidence base for this indication rests almost entirely on open-label trials, leaving open the possibility...
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A review of major clinical trials in cardiovascular medicine.
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