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Latest Issues

Amyloid or not Amyloid?

Something is really bugging me, and I need to think it through out loud to get my thoughts in order.

This article is not intended to provide alternative explanations for the poorly soluble microclots, even though an alternative–such as im...

13 days ago
7
4

Even more sceptical

I have some more questions about the experimental design in terms of methodology and correlation. What exactly is a double-filtration apheresis supposed to prove to me if my focus was exclusively on β-amyloid-like clots? I will subgroup thi...

19 days ago
6
22

Skeptical

https://x.com/kevinmccairnphd/status/2047314305948008929?s=52&t=fHNy04S5p-78vK_ah9g3hw

Example for feedforward & feedback loop for MAPK(ERK)-Pathway and mTORC1 crosstalks with electrostatic/ dieelectric interactions.1, 2 PI3K gets attracte...

25 days ago
3

Am I Crazy (Part 2)?

I’m racking my brain and thinking at my limit right now! In part one, I raised two questions:

What function would normally hydrophilic DNA fulfill in an LNP that relies on hydrophobic effects? Are there any clues?

Was it purely unintenden...

a month ago
9
9

Am I crazy?

See what this paper from Wiebe et al.1 is telling you?: There is an interdependence between Lipid-composition and modRNA-formulation. Although the authors speculate that this is due to the composition of the frozen lipid kinetic minimum its...

a month ago
10
5

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  • Genervter Bürger

    Nothing to see here cause I am a layman

  • The Offsc℞ipt Pharmacist

    Off label analysis from a pharmacist who reads the fine print. Independent researcher. Independent thinker. Wife, mother, grandmother, Catholic.

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