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Long Happy Life

Claire Machado

Essays on health, science, longevity, and biohacking.

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Substack
PricingOnly free issuesPublishesWeekly
Issues22Foundeda year agoLast Issue2 days ago
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Latest Issues

Does the chair undo the workout?


I’ve mentioned before that I’m always taking part in some kind of study. Usually it’s a supplement study, where I take one or several for three months and go through some very thorough blood work, or epigenetic and metabolomic testin...

2 days ago
5
2

Fortnightly Finds 01


This is the first post of the new series Fortnightly Finds. Every two weeks, I'll bring you two longevity and science news stories, chosen and commented on by me.


Eating within 8 hours might help our brain stay sharp as we...

10 days ago
5
1

The brain outside the cloud


I started watching the 2026 reboot of Little House on the Prairie. If you grew up with it (yeah, I'm from that time), you probably remember the original from 1974, still streaming today.1

And I noticed something that inspired me to...

17 days ago
13
2

How not to melt this summer


I’m writing this from Georgia, US, in the middle of a heat wave, so if your summer looks different or hasn’t shown up yet, save this for when it does. If you read Smart Hydration, you already know sweating means losing more than wate...

a month ago
10
3

The science of gathering



We're four weeks into the World Cup now, which feels like the right moment for this. There's something bigger happening when people gather around those games. Something that has nothing to do with the sport itself.

It’s 8:...

2 months ago
20
11

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  • Claire Machado

    Science, longevity, and biohacking for real life. 17 years of research and experimentation. I write Vida Longa e Feliz (in Portuguese), Long Happy Life (in English), and Microdose Longevity (bilingual).

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