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Neurostats

Manjari Narayan

Dissecting the science of brains, behavior and medicine with the methodologist's razor.

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Issues15Founded6 years agoLast Issue9 months ago
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Latest Issues

Neurostats Digest #6

November 16, 2025

As every disease area pins its hopes on blood biomarkers, it is instructive to see what these tests are actually being used for in Alzheimer’s.

It strikes me that the current usage of blood biomarkers in dementia will be...

9 months ago
1

Request for Information: Synthetic Datasets

TL;DR; If you know something about this, have written or read papers on this please comment.

There are broadly two approaches to analyze data and distribute results when the data is not available to share for legal and privacy reasons....

9 months ago
3

Misunderstandings between empirical and theoretical scientists

Definition: When scientists think X is a mathematically proven theorem and mathematicians think X is an empirical determined fact.

Many years ago, I began calling this type of situation the Poincaré-Lippman gap. I first used it publicly in...

9 months ago
27
3

Neurostats Digest #5

Contents

  • Markers of psychiatric disorders are neither necessary nor sufficient

  • Modern causal inference for psychiatric kinds

  • Subjectivity is not the problem for psychiatric endpoints

  • The papers that change you

  • The...

10 months ago
4
1

Biomarker Qualification

Definition: Biomarker qualification is about thinking through the full chain of evidence to prove that a biomarker can be used for a particular clinical decision.

HDL serum cholesterol, for instance, is great for evaluating risk of heart...

a year ago
5

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  • Manjari Narayan

    Creating an abundance of rigor. Interests include developing scientific reasoning benchmarks, forecasting methodological discovery and surrogate science. ECE PhD at Rice. Previously: Stanford, DynoTx, SpecTech Fellow. Causal AI, neurotech, biotech.

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