NeuroLipid Notebook
Nurse Jeannie CaponeA precision brain-reserve protocol using MFSD2A, LPC DHA, and lipid-pathway optimization for APOE4 carriers, cognitive resilience. A resource for forward-thinking clinicians and researchers.
| Platform |  | Pricing | Freemium | Publishes | Daily |
|---|---|---|---|---|---|
| Issues | 64 | Subscribers | Read | neurolipidnotebook.substack.com |
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Latest Issues
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The Three-Hit Model: Why APOE4 Alone Doesn’t Explain the Brain’s DHA Deficit
FADS genotype, APOE4 catabolism, and dietary linoleic acid may converge to create a progressive, age-dependent failure of brain DHA incorporation — and the data to test it already exist.
Start Here: An ApoE4 Centered Model for Understanding Brain Health
If you’re new, this isn’t a newsletter about supplements. This isn’t a Substack where I’m going tell you what supplements I take as an ApoE4 carrier every week.
The DHA Didn’t Miss the Brain — It Wasn’t Incorporated
Jeannie Capone, BS, MSN, FNP-BC, PMHNP-BC
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Authors
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I explore translational approaches to brain health, lipid biology, and cognitive resilience. This publication tracks personal experiments and distills emerging science aimed at optimizing neurovascular and mitochondrial function.
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