Better Microbiome Thinking
William DePaolo PhDEssays by William DePaolo, PhD on how the gut, brain, and environment shape one another. Exploring microbiome science beyond “good vs. bad bacteria” toward systems thinking, integration, and human meaning.
| Platform |  | Pricing | Freemium | Publishes | Daily |
|---|---|---|---|---|---|
| Issues | 60 | Subscribers | Read | williamdepaolo.substack.com |
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Latest Issues
Recent posts by this newsletter. Browse the email archive.
HYPE WATCH: "Global experts establish first scientific definition of gut health”
This Nutrition Insight write-up (link below) is a perfect specimen. It’s not screaming misinformation. It’s doing something more effective. It’s upgrading a consensus framework into a breakthrough story using a handful of predictable phrase...
Normal for Whom? The ISAPP Gut Health Consensus Problem
This 2026 ISAPP consensus statement (https://www.nature.com/articles/s41575-026-01176-x) says it’s trying to “clarify” gut health for clinicians, regulators, industry, and the public. It makes the whole thing sound clearer than it actually ...
The Cold Math of Hiring
This is a bit of a deviation from my normal subject matter here at Better Microbiome Thinking. But this has been on my mind for a while….
Postbiotics: the calm, dead cousin of probiotics
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Authors
The writers behind this newsletter.
Essays by William DePaolo, PhD on how the gut, brain, and environment shape one another. Exploring microbiome science beyond “good vs. bad bacteria” toward systems thinking, integration, and human meaning.
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