Better Microbiome Thinking
William DePaolo PhDUnderstand your microbiome, avoid the hype, and make smarter health decisions with evidence you can actually use.
| Platform |  | Pricing | Freemium | Publishes | Daily |
|---|---|---|---|---|---|
| Issues | 119 | Founded | a year ago | Last Issue | 6 days ago |
| Active | |||||
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williamdepaolo.substack.comLatest Issues
When the Biology Doesn’t Quite Fit: Thoughts on the Russian Pneumonic Plague Investigation
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Early in my scientific career, I worked with Yersinia pestis, the bacterium responsible for plague. It is one of those organisms that commands immediate respect in a laboratory. Not because it is mysterious, but because decad...
Does Your Microbiome Test Change the Advice or Just the Price?
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Imagine paying for a microbiome test, waiting for the report, and opening a personalized plan that tells you to eat more plants, increase your fiber intake, and consider a supplement. Before changing your breakfast, ask the c...
Dysbiosis and the Art of Explaining Nothing
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“Dysbiosis” has a remarkable talent for making an unfinished explanation sound like a completed diagnosis. The bacteria are different, so the microbiome is dysbiotic. The patient is sick, so the dysbiosis must matter. A produ...
Who Gets Protected When Microbiome Companies Stay Anonymous?
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Imagine paying for a microbiome test because you want an explanation for what is happening in your body. You send away a stool sample and receive a report describing your bacteria, assessing your gut health and suggesting cha...
Your gut reset has an end date. Does it have a definition of success?
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By day seven, you can finish every powder, follow every food rule, and complete your gut reset exactly as instructed. The company can count a sale, and you can count a week of effort. What would either of you measure to estab...
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| Subscribers | Engagement | 73 | Monthly Web Visits | ||
|---|---|---|---|---|---|
| Accepts Sponsors | Estimated Cost per Ad | ||||
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Authors
The writers behind this newsletter.
Essays by William DePaolo, PhD on how the gut, brain, and environment shape one another. Exploring microbiome science beyond “good vs. bad bacteria” toward systems thinking, integration, and human meaning.
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