Better Microbiome Thinking
William DePaolo PhDEssays by William DePaolo, PhD on how the gut, brain, and environment shape one another. Exploring microbiome science beyond “good vs. bad bacteria” toward systems thinking, integration, and human meaning.
| Platform |  | Pricing | Freemium | Publishes | Daily |
|---|---|---|---|---|---|
| Issues | 97 | Founded | 9 months ago | Last Issue | 7 days ago |
| Active | |||||
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williamdepaolo.substack.comLatest Issues
The Global Microbiome Conservancy Expands the Map. It Does Not Solve the Field.
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Janeen Interlandi’s July 8th 2026 New York Times Magazine article "Our Bacteria Are Talking. We've Just Begun to Understand What They're Saying" is a serious and valuable piece of microbiome journalism. It exposes one of the...
Seven Microbiome Companies Failed a Public Test. Why Are Their Names Still Hidden?
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A study showed that seven direct-to-consumer microbiome testing companies could analyze the same standardized stool material and return meaningfully different results.
Then nothing happened.
No public company-by-company acc...
Your Microbiome Score Is Not a Health Score
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The wellness industry has turned a stool sample into a personality test with a checkout page.
You mail in a small plastic tube of shit. A company runs sequencing. A dashboard appears.
Then comes the verdict:
Your gut healt...
Probiotic Evidence Ledger
What specific strains have actually been studied, what they were studied for, and where the evidence stops
Walk into a pharmacy, grocery store, or aggressively beige wellness website and you will meet the same promise in different fonts:
Every Probiotic Label Should Answer These Five Questions. Most Don’t.
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The probiotic aisle is built to make you feel underinformed.
The labels are crowded. The organisms have long names. The numbers are enormous. The claims are fuzzy enough to sound medically important without saying anything m...
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| Subscribers | Engagement | 74 | Monthly Web Visits | ||
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| Accepts Sponsors | Estimated Cost per Ad | ||||
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Essays by William DePaolo, PhD on how the gut, brain, and environment shape one another. Exploring microbiome science beyond “good vs. bad bacteria” toward systems thinking, integration, and human meaning.
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