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Better Microbiome Thinking

William DePaolo PhD

Understand your microbiome, avoid the hype, and make smarter health decisions with evidence you can actually use.

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Issues108Founded10 months agoLast Issue8 days ago
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Latest Issues

Your Microbiome Test Does Not Know What Your Gut Bacteria Are Doing

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Microbiome tests can find bacteria. Personalized diet reports often ask those results to predict an entire biological chain the assay never measured.

In February 2026, researchers from the National Institute of Standards and...

8 days ago
1

The Complete Guide to Interpreting Your Microbiome Test Results

Definitive guide | July 2026

A microbiome report can look more precise than the science beneath it.

You send a stool sample to a laboratory. A few weeks later, a polished dashboard appears. It assigns you a diversity score. It ranks your...

13 days ago
1

How to Evaluate Microbiome Tests, Probiotics, and Gut Health Claims

Why this framework exists

Microbiome information often arrives as a conclusion before it arrives as evidence. A headline says a bacterium causes a disease. A test promises a personalized plan. A probiotic claims to support gut health. A...

13 days ago
3

Tools and Products

I created practical resources that help consumers and health professionals understand microbiome science, evaluate gut health claims, and make better decisions. Each resource is designed to turn complicated research into useful questions an...

15 days ago

Your Probiotic Face Cream Is Probably Microbiome Theater

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The beauty industry has discovered a remarkable business model.

Take a young science. Remove the uncertainty. Put it in a bottle. Call it balance.

I have worked in microbiome science for more than fifteen years. I believe m...

16 days ago
2
2

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  • William DePaolo PhD

    Essays by William DePaolo, PhD on how the gut, brain, and environment shape one another. Exploring microbiome science beyond “good vs. bad bacteria” toward systems thinking, integration, and human meaning.

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