
A FREE newsletter navigating APOE4, exploring the science of Alzheimer's prevention, biomarkers, and lifelong brain health. Stay abreast of the newest developments - completely FREE!
| Platform | Pricing | Only free issues | Publishes | Weekly | |
|---|---|---|---|---|---|
| Issues | 79 | Founded | a year ago | Last Issue | 11 days ago |
| Active | |||||

As most of you know, I recently went back for my brain health and APOE4-focused assessments at RetainMed in Boca Raton to meet with specially trained Nurse Practitioners utilizing Dr. Richard Isaacson’s precision prevention methodology, and...
If you’ve been following my writing for a while, Obicetrapib is a name you’ve become familiar with.
In a previous post, I explained what CETP inhibition is and how it protects the brain and cardiovascular system. The biology is very intrig...
Some very exciting news for those of us who have been following obicetrapib, the new oral CETP inhibitor developed by NewAmsterdam Pharma.
Today, September 21, 2026, the European Commission granted marketing authorization for obicetrapib,...
In the years I’ve been researching the APO...
Some fascinating new research out of Stockholm University is looking at something we don’t normally associate with Alzheimer’s disease: the liver.
The researchers are investigating whether APOE4 produced in the liver may contribute to Alzh...
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The writers behind this newsletter.
APOE4/4 biohacker and lifelong learner sharing so you don’t start from zero. For APOE4 carriers, families, and curious clinicians. Evidence-guided, practical prevention - checklists, N=1 notes, and optimism for brain health and bold living.
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