The APOE4 Gene | Brain Health & Alzheimer’s Prevention
Karin DeeHealth-Focused / APOE4-Oriented: Insights, strategies, and lived experience to outsmart APOE4, reduce AD risk, and excel —vibrantly, intelligently, and on your own terms.
| Platform |  | Pricing | Only free issues | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 43 | Subscribers | Read | apoe44.org |
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Latest Issues
Recent posts by this newsletter. Browse the email archive.
Lipid Replacement Therapy (LRT): Rebuilding Cell Membranes From the Ground Up
In APOE4 Revealing Its Hand, I focused on how APOE4 alters lipid transport and metabolism; here, I want to step back and examine something even more fundamental - the lipid architecture that makes neural signaling, repair, and resilience po...
APOE4 Is Revealing Its Hand
For a long time, APOE4 sat in an uncomfortable scientific limbo.
My APOE4/4 Senolytic Protocol: Intermittent pulsing of Fisetin/Quercetin/Dasatinib to kill off "zombie" cells.
Alzheimer’s disease is usually discussed in terms of amyloid and tau. But those pathologies do not arise in isolation. Aging biology sets the stage — and one of the most consequential, yet under-appreciated, contributors to age-related dise...
Botox and APOE4:
This is a question I’ve seen posed often, especially from APOE4 carriers who are thoughtful—sometimes understandably anxious—about anything that could affect brain health.
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Authors
The writers behind this newsletter.
APOE4/4 biohacker and lifelong learner sharing so you don’t start from zero. For APOE4 carriers, families, and curious clinicians. Evidence-guided, practical prevention—checklists, N=1 notes, and optimism for brain health and bold living.
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