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APOE4 & Alzheimer’s Prevention | Brain Health Science

Karin Dee

A FREE newsletter navigating APOE4, exploring the science of Alzheimer's prevention, biomarkers, and lifelong brain health. Stay abreast of the newest developments - completely FREE!

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Issues79Foundeda year agoLast Issue11 days ago
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Latest Issues

A Deeper Dive Into the Results From My RetainMed Visit

As most of you know, I recently went back for my brain health and APOE4-focused assessments at RetainMed in Boca Raton to meet with specially trained Nurse Practitioners utilizing Dr. Richard Isaacson’s precision prevention methodology, and...

11 days ago
22
9

Obicetrapib: Why There Is So Much Excitement Over The Release Of This Drug.

If you’ve been following my writing for a while, Obicetrapib is a name you’ve become familiar with.

In a previous post, I explained what CETP inhibition is and how it protects the brain and cardiovascular system. The biology is very intrig...

18 days ago
19
4

Obicetrapib Just Received European Approval

Some very exciting news for those of us who have been following obicetrapib, the new oral CETP inhibitor developed by NewAmsterdam Pharma.

Today, September 21, 2026, the European Commission granted marketing authorization for obicetrapib,...

21 days ago
16
2

A New Clue Emerges How APOE4 Damages the Blood-Brain Barrier

New research identifies fibronectin as a potential link between APOE4, inflammation and blood-brain barrier dysfunction—and points toward some intriguing possibilities for prevention research.

In the years I’ve been researching the APO...

25 days ago
13
12

Interesting New APOE4 Research Which Takes Me Back to Dr. Alan Green and Rapamycin

Some fascinating new research out of Stockholm University is looking at something we don’t normally associate with Alzheimer’s disease: the liver.

The researchers are investigating whether APOE4 produced in the liver may contribute to Alzh...

a month ago
21
10

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  • Karin Dee

    APOE4/4 biohacker and lifelong learner sharing so you don’t start from zero. For APOE4 carriers, families, and curious clinicians. Evidence-guided, practical prevention - checklists, N=1 notes, and optimism for brain health and bold living.

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