Midlife Brain Project
Dr Mark ChernLooking for words? Foggy brain? Let’s work at preventing dementia 20 years earlier.
| Platform |  | Pricing | Only free issues | Publishes | Twice weekly |
|---|---|---|---|---|---|
| Issues | 96 | Founded | 3 years ago | Last Issue | 2 days ago |
| Active | |||||
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drmarkchern.substack.comLatest Issues
The Cold Plunge Cortisol Study Everyone Cites, and What It Actually Says About Women’s Brains
Source: Garden of Life
There’s a claim moving through women’s health circles right now, and it goes roughly like this:
cold plunging spikes cortisol
—> chronically elevated cortisol damages the female brain
—> therefore cold plunging...
She Should Have Gotten Alzheimer's by 49. Something Stopped It.
There’s a mutation in Colombia that has never once failed to cause Alzheimer’s. Not once, across thousands of people, for generations.
I happened to spend a month in that same region last year, with no idea what I was walking near.
Then...
Does Sauna Really Lower Dementia Risk by 66%?
There’s a stat I keep running into everywhere. Sauna 4-7x a week, and your dementia risk drops 66%. It’s in longevity newsletters, on podcasts, in the marketing copy for basically every home sauna being sold right now. Same number, every si...
Donepezil vs Memantine vs Leqembi vs Kisunla for Alzheimer’s: The One That Actually Wins
Source: SciTechDaily
Someone gets a diagnosis. A doctor offers a drug. The family goes home and searches the name, wanting a simple answer: does this work, and what will it do to me?
That’s surprisingly hard to answer, since the four main...
Donepezil, Rivastigmine, Galantamine: Do They Slow Alzheimer's or Just Treat Symptoms?
What’s always struck me about Alzheimer’s drug history is how often the interesting part isn’t the drug itself, it’s the moment researchers realize a mechanism they thought they understood was doing something else entirely, usually years af...
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| Subscribers | Engagement | 70 | Monthly Web Visits | ||
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| Accepts Sponsors | Estimated Cost per Ad | ||||
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Authors
The writers behind this newsletter.
I am Dr Mark and I am in my 40s. I had a scare 2+years ago when my memory was clearly deteriorating. After making deliberate changes, I am now back on track. But was that scary!
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