In-depth analysis & opinion of startups, innovation, venture capital, & entrepreneurship. "This read right here is better than half the classes at most incubators and 1000% better than any entrepreneur course at a university." Nicolia Wiles - PRIMEPR
| Platform |  | Pricing | Only free issues | Publishes | Daily |
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paulobrien.substack.comLatest Issues
Midwest Startups Built America from the Basement; Now the Heartland Fixes Entrepreneurship
One of my favorite memories of growing up was how we built from our basement. For me that was in Michigan, (a state from which I’m going to deviate a bit in exploring this part of the world); that, in appreciating that entrepreneurial peopl...
Healthcare, Government, HR, and Education Innovation Keeps Failing for One Reason; The Sectors That Shape Your Life Were Built to Control It
In 2016, the U.S. Government Accountability Office reported that the Department of Defense was coordinating America’s nuclear forces on a 1970s IBM computer that stored data on 8-inch floppy disks. The same review found the federal governme...
HR Tech 2026 in Las Vegas Is Where the Future of Work is Learning to Read the Data It Already Owns
I have been spending a lot of time thinking about the future of work. Whether in the context of our startups and founders meaningfully creating jobs, as they do mostly, in the context of how we work, or in the context of workforce solutions...
The Next Version of the Startup Accelerator Is Being Drafted in New York at AcceleratorCON
On May 17, 1792, 24 New York merchants and brokers stood under a buttonwood tree near what became Wall Street and agreed to trade securities, only with one another, at fixed commissions. The Buttonwood Agreement became the New York Stock Ex...
Among Losers Who Raised as Much as the Winners we Find a Startup Moat That Too Few Build
Research has spent twenty years telling us that the team and the marketing work cause most startup successes and failures. The AI boom is now nudging investors, advisors, and founders toward the same lesson but the hard way: in a market whe...
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Authors
The writers behind this newsletter.
Author of Startup Ecosystems; Managing Director of Startup Economist. I help cities build startup ecosystems that work.
Ruthann Peace Brown is an educator, entrepreneur, author of Unlock Your World, and advocate for the human side of performance.
Founder, Investor, Mentor, Scholar | Calling babies ugly since 1999 | ABD on my EdD at ASU Mary Lou Fulton College for Teaching and Learning Innovation
Hi, I love training mental and emotional strength for people who build things.
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