Letters from a Pharmacist
J Gamble, PhD RPhCritical drug evidence, distilled into practical pharmacotherapy insight.
| Platform |  | Pricing | Freemium | Publishes | Weekly |
|---|---|---|---|---|---|
| Issues | 53 | Founded | a year ago | Last Issue | 5 days ago |
| Active | |||||
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jmgamble.substack.comLatest Issues
Testosterone Pharmacotherapy Pearls for Older Men
Dear Reader,
This week I am writing about testosterone therapy for older men with hypogonadism. This was inspired by working with PharmD students last week on men’s health cases during their therapeutics tutorial. Here are three clinical p...
Letters from a Pharmacist — Year One
Dear Readers,
The first Letters from a Pharmacist post was on June 2nd, 2025 and after one-year of writing these letters, I find myself reflecting on the way forward.
I’ve been reflecting on the value proposition of Letters from a Pharma...
Generic semaglutide is here but not your typical generic
Dear Readers,
A brief letter this week! May is the busiest teaching month of the year on my end which means less time for writing but I love interacting with all of the students!
In this letter, I will write about a few interesting point...
Interpreting composite endpoints in health research
Dear Reader,
Composite endpoints show up everywhere in modern clinical trials. Instead of hanging the results on a single outcome, researchers often bundle several clinically related events together and analyze them as one. That can be gen...
Three high-alert drugs in primary care
Dear Reader,
Many drugs have the potential to cause harm. Here is my list of the top 3 drug classes that are likely to cause harm in primary care.
I have selected these drugs from the Canadian High-Alert Medication List from ISMP Canada....
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Authors
The writers behind this newsletter.
I am a health scientist writing about drug evidence, what it shows, what it doesn’t, and what often gets lost in translation. Independent, evidence-first. Pharmacoepidemiologist | Pharmacist | Clinical Associate Professor
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