Letters from a Pharmacist
J Gamble, PhD RPhCritical drug evidence, distilled into practical pharmacotherapy insight.
| Platform |  | Pricing | Only free issues | Publishes | Weekly |
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| Issues | 58 | Founded | 2 years ago | Last Issue | 12 days ago |
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jmgamble.substack.comLatest Issues
Metformin in Type 2 Diabetes: Still the Right First Step?
Dear Reader,
Earlier this year in one of our research group meetings we discussed the updated NICE guidelines for type 2 diabetes. That conversation resurfaced a question that comes up regularly when I teach in the classroom and the clinic...
Clinical Pearls on Finerenone
Finerenone (Kerendia®) is often grouped with older mineralocorticoid receptor antagonists such as spironolactone and eplerenone, but it is a distinct drug, with a different pharmacologic profile, a growing list of indications, and evidence...
Bias in RCTs - Part 5 (SPIN)
Dear Reader,
While researching Part 4 of this series, I came across two classic examples of interpretive spin that highlight the difference between reporting results and interpreting them.
Interpretive spin occurs when study results are f...
A Summer Hiatus
Dear Readers,
This summer is nearly over as evident by the cooler mornings and children back in school. As some of you may have noticed, I took a hiatus from writing these letters over July and August. And every hiatus has a trail of stori...
Bias in RCTs - part 4
Bias in the selection of the reported result
Dear Reader,
Welcome to Part 4 of a series of letters on bias in RCTs.
Part 4 covers bias in selection of reported results. This bias arises when a published result is chosen, based on its di...
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Authors
The writers behind this newsletter.
I am a health scientist writing about drug evidence, what it shows, what it doesn’t, and what often gets lost in translation. Independent, evidence-first. Pharmacoepidemiologist | Pharmacist | Clinical Associate Professor
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